NEUROSHIELD
CHITOSAN MEMBRANE
- Transparent for better visualization
- Non-sided for easier placement
- Easy to suture and resistant to pull-out
- Soft, pliable and conforms to tissue
- Two sizes protect nerve diameters up to 9 mm and 12 mm
BIORESORPTION COMPATIBLE WITH THE TISSUE HEALING CASCADE
NeuroShield’s chitosan hydrogel structure supports and protects the underlying nerve structure during soft tissue healing. Over time, the chitosan membrane naturally resorbs, degrading into compounds that may be beneficial for nerve regeneration.1-3
CLINICAL APPLICATIONS
NEUROSHIELD AND CHITOSAN:
THE DEVELOPER'S PERSPECTIVE
Dr. Thomas Freier, co-developer of NeuroShield, shares his thoughts about chitosan and its use in the NeuroShield Chitosan Nerve Wrap.
Request a demo or product trial
Helpful Resources
References
- Carvalho CR, López-Cebral R, Silva-Correia J, Silva JM, Mano JF, Silva TH, Freier T, Reis RL, Oliveira JM. (2017). Investigation of cell adhesion in chitosan membranes for peripheral nerve regeneration. Materials Science and Engineering: C, 71, 1122–1134.
- Wang Y, Zhao Y, Sun C, Hu W, Zhao J, Li G, Zhang L, Liu M, Liu Y, Ding F, Yang Y, Gu X. (2016). Chitosan degradation products promote nerve regeneration by stimulating schwann cell proliferation via miR-27a/FOXO1 Axis. Mol Neurobiol. 2016 Jan;53(1):28-39.
- Zhao Y, Wang Y, Gong J, Yang L, Niu C, Ni X, Wang Y, Peng S, Gu X, Sun C, Yang Y. (2017). Chitosan degradation products facilitate peripheral nerve regeneration by improving macrophage constructed microenvironments. Biomaterials, 134, 64–77.
