
Corrugated Design
The corrugated wall structure flexes with movement while maintaining an open, unobstructed lumen, protecting the regenerating nerve without restricting natural tissue motion.3
Type I Collagen Matrix
Biocompatible and resorbable, Type 1 collagen supports the regenerative environment nerves need and is resorbed via normal metabolic pathways.1
Protective Neural Environment
Provides a protective environment for peripheral nerve repair after injury, allowing for small-sized nutrients and neurotrophic factors to pass through the matrix while blocking larger molecules like fibroblasts, supporting Schwann cell migration and axonal regeneration.2,4
Nerve Preparation Forceps
Every conduit is packaged with purpose-designed nerve preparation forceps, built to preserve fascicular alignment and tissue integrity during nerve end preparation prior to conduit placement.5,6
AxioCor’s corrugated design allows the conduit to flex with natural tissue movement while maintaining an open, unobstructed lumen throughout.
Bends up to 60° without occlusion, while standard conduits and connectors occlude at 20°.3
Includes a microsurgical background to support consistent preparation and visibility of nerve tissue.

Employs circumferential constraint to maintain the nerve’s natural shape during nerve end preparation. Constraining the nerve in this manner prevents nerve sliding, flattening, and subsequent nerve edge malformation, preserving fascicular group alignment and tissue integrity.5,6


Animal study data on file at Collagen Matrix, Inc.
Li ST, Archibald SJ, Krarup C, Madison RD. Peripheral nerve repair with collagen conduits. Clin Mater. 1992;9(3-4):195-200.
Yuen D, Jensen JR, Rodriguez G, and Li ST. A semipermeable, kink resistant type I collagen-based nerve guide for PNS repair. Trans Soc Biomaterials. 2003:228.
U.S Patent #6,716,225, Implant Devices for Nerve Repair, 2004.
Smetana B, et al. Improving Nerve End Preparation for Neurorrhaphy through Use of a Circumferentially Constraining Surgical Device. Poster presented at 2018 ASPN Annual Meeting, January 12-14, 2018, Phoenix, AZ.
Jernigan EW, Patterson JMM, Draeger RW. How to cut a nerve: morphological implications of instruments used in preparation of severed nerves for neurorrhaphy. J Hand Surg Eur Vol. 2017;42(9):961-963.
0136-MKT-199-A


